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Myosin Light Chain Kinase Mediates Intestinal Barrier Disruption following Burn Injury

BACKGROUND: Severe burn injury results in the loss of intestinal barrier function, however, the underlying mechanism remains unclear. Myosin light chain (MLC) phosphorylation mediated by MLC kinase (MLCK) is critical to the pathophysiological regulation of intestinal barrier function. We hypothesize...

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Detalles Bibliográficos
Autores principales: Chen, Chuanli, Wang, Pei, Su, Qin, Wang, Shiliang, Wang, Fengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329538/
https://www.ncbi.nlm.nih.gov/pubmed/22529961
http://dx.doi.org/10.1371/journal.pone.0034946