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Did Clinical Trials in Which Erythropoietin Failed to Reduce Acute Myocardial Infarct Size Miss a Narrow Therapeutic Window?

BACKGROUND: To test a hypothesis that in negative clinical trials of erythropoietin in patients with acute myocardial infarction (MI) the erythropoietin (rhEPO) could be administered outside narrow therapeutic window. Despite overwhelming evidence of cardioprotective properties of rhEPO in animal st...

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Detalles Bibliográficos
Autores principales: Talan, Mark I., Ahmet, Ismayil, Lakatta, Edward G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329541/
https://www.ncbi.nlm.nih.gov/pubmed/22529941
http://dx.doi.org/10.1371/journal.pone.0034819