Downstream and Intermediate Interactions of Synovial Sarcoma-Associated Fusion Oncoproteins and Their Implication for Targeted Therapy

Synovial sarcoma (SS), an aggressive type of soft tissue tumor, occurs mostly in adolescents and young adults. The origin and molecular mechanism of the development of SS remain only partially known. Over 90% of SS cases are characterized by the t(X;18)(p11.2;q11.2) translocation, which results main...

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Detalles Bibliográficos
Autores principales: Przybyl, Joanna, Jurkowska, Monika, Rutkowski, Piotr, Debiec-Rychter, Maria, Siedlecki, Janusz A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329658/
https://www.ncbi.nlm.nih.gov/pubmed/22550415
http://dx.doi.org/10.1155/2012/249219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329658/
https://www.ncbi.nlm.nih.gov/pubmed/22550415
http://dx.doi.org/10.1155/2012/249219

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