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Downstream and Intermediate Interactions of Synovial Sarcoma-Associated Fusion Oncoproteins and Their Implication for Targeted Therapy
Synovial sarcoma (SS), an aggressive type of soft tissue tumor, occurs mostly in adolescents and young adults. The origin and molecular mechanism of the development of SS remain only partially known. Over 90% of SS cases are characterized by the t(X;18)(p11.2;q11.2) translocation, which results main...
Autores principales: | Przybyl, Joanna, Jurkowska, Monika, Rutkowski, Piotr, Debiec-Rychter, Maria, Siedlecki, Janusz A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329658/ https://www.ncbi.nlm.nih.gov/pubmed/22550415 http://dx.doi.org/10.1155/2012/249219 |
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