Colesevelam Improves Oral but Not Intravenous Glucose Tolerance by a Mechanism Independent of Insulin Sensitivity and β-Cell Function

OBJECTIVE: To determine the mechanism by which the bile acid sequestrant colesevelam improves glycemic control. RESEARCH DESIGN AND METHODS: We performed a frequently sampled intravenous glucose tolerance test (FSIGT) with minimal model analysis and a meal tolerance test (MTT) in 20 subjects with im...

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Detalles Bibliográficos
Autores principales: Marina, Anna L., Utzschneider, Kristina M., Wright, Lorena A., Montgomery, Brenda K., Marcovina, Santica M., Kahn, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329824/
https://www.ncbi.nlm.nih.gov/pubmed/22446171
http://dx.doi.org/10.2337/dc11-2050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329824/
https://www.ncbi.nlm.nih.gov/pubmed/22446171
http://dx.doi.org/10.2337/dc11-2050

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