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Colesevelam Improves Oral but Not Intravenous Glucose Tolerance by a Mechanism Independent of Insulin Sensitivity and β-Cell Function
OBJECTIVE: To determine the mechanism by which the bile acid sequestrant colesevelam improves glycemic control. RESEARCH DESIGN AND METHODS: We performed a frequently sampled intravenous glucose tolerance test (FSIGT) with minimal model analysis and a meal tolerance test (MTT) in 20 subjects with im...
Autores principales: | Marina, Anna L., Utzschneider, Kristina M., Wright, Lorena A., Montgomery, Brenda K., Marcovina, Santica M., Kahn, Steven E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329824/ https://www.ncbi.nlm.nih.gov/pubmed/22446171 http://dx.doi.org/10.2337/dc11-2050 |
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