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Skin-Derived Precursor Cells as an In Vitro Modelling Tool for the Study of Type 1 Neurofibromatosis

The most characteristic feature of neurofibromatosis type 1 (NF1) is the development of neurofibromas. It has been suggested that these tumors are caused by somatic inactivation of the wild-type NF1 allele, but the cell that originally suffers this mutation remains controversial. Several lines of ev...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Rivera, Araika, Iribar, Haizea, Tuneu, Anna, Izeta, Ander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329859/
https://www.ncbi.nlm.nih.gov/pubmed/22550514
http://dx.doi.org/10.1155/2012/646725