Functional interplay between p53 acetylation and H1.2 phosphorylation in p53-regulated transcription

Linker histone H1.2 has been shown to suppress p53-dependent transcription through the modulation of chromatin remodeling; however, little is known about the mechanisms governing the antagonistic effects of H1.2 in DNA damage response. Here we show that the repressive action of H1.2 on p53 function...

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Detalles Bibliográficos
Autores principales: Kim, Kyunghwan, Jeong, Kwang Won, Kim, Hyunjung, Choi, Jongkyu, Lu, Wange, Stallcup, Michael R., An, Woojin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330162/
https://www.ncbi.nlm.nih.gov/pubmed/22249259
http://dx.doi.org/10.1038/onc.2011.605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330162/
https://www.ncbi.nlm.nih.gov/pubmed/22249259
http://dx.doi.org/10.1038/onc.2011.605

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