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GLUT4 and Glycogen Synthase Are Key Players in Bed Rest–Induced Insulin Resistance

To elucidate the molecular mechanisms behind physical inactivity–induced insulin resistance in skeletal muscle, 12 young, healthy male subjects completed 7 days of bed rest with vastus lateralis muscle biopsies obtained before and after. In six of the subjects, muscle biopsies were taken from both l...

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Detalles Bibliográficos
Autores principales: Biensø, Rasmus S., Ringholm, Stine, Kiilerich, Kristian, Aachmann-Andersen, Niels-Jacob, Krogh-Madsen, Rikke, Guerra, Borja, Plomgaard, Peter, van Hall, Gerrit, Treebak, Jonas T., Saltin, Bengt, Lundby, Carsten, Calbet, Jose A.L., Pilegaard, Henriette, Wojtaszewski, Jørgen F.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331744/
https://www.ncbi.nlm.nih.gov/pubmed/22403297
http://dx.doi.org/10.2337/db11-0884