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No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels

Gene–lifestyle interactions have been suggested to contribute to the development of type 2 diabetes. Glucose levels 2 h after a standard 75-g glucose challenge are used to diagnose diabetes and are associated with both genetic and lifestyle factors. However, whether these factors interact to determi...

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Autores principales: Scott, Robert A., Chu, Audrey Y., Grarup, Niels, Manning, Alisa K., Hivert, Marie-France, Shungin, Dmitry, Tönjes, Anke, Yesupriya, Ajay, Barnes, Daniel, Bouatia-Naji, Nabila, Glazer, Nicole L., Jackson, Anne U., Kutalik, Zoltán, Lagou, Vasiliki, Marek, Diana, Rasmussen-Torvik, Laura J., Stringham, Heather M., Tanaka, Toshiko, Aadahl, Mette, Arking, Dan E., Bergmann, Sven, Boerwinkle, Eric, Bonnycastle, Lori L., Bornstein, Stefan R., Brunner, Eric, Bumpstead, Suzannah J., Brage, Soren, Carlson, Olga D., Chen, Han, Chen, Yii-Der Ida, Chines, Peter S., Collins, Francis S., Couper, David J., Dennison, Elaine M., Dowling, Nicole F., Egan, Josephine S., Ekelund, Ulf, Erdos, Michael R., Forouhi, Nita G., Fox, Caroline S., Goodarzi, Mark O., Grässler, Jürgen, Gustafsson, Stefan, Hallmans, Göran, Hansen, Torben, Hingorani, Aroon, Holloway, John W., Hu, Frank B., Isomaa, Bo, Jameson, Karen A., Johansson, Ingegerd, Jonsson, Anna, Jørgensen, Torben, Kivimaki, Mika, Kovacs, Peter, Kumari, Meena, Kuusisto, Johanna, Laakso, Markku, Lecoeur, Cécile, Lévy-Marchal, Claire, Li, Guo, Loos, Ruth J.F., Lyssenko, Valeri, Marmot, Michael, Marques-Vidal, Pedro, Morken, Mario A., Müller, Gabriele, North, Kari E., Pankow, James S., Payne, Felicity, Prokopenko, Inga, Psaty, Bruce M., Renström, Frida, Rice, Ken, Rotter, Jerome I., Rybin, Denis, Sandholt, Camilla H., Sayer, Avan A., Shrader, Peter, Schwarz, Peter E.H., Siscovick, David S., Stančáková, Alena, Stumvoll, Michael, Teslovich, Tanya M., Waeber, Gérard, Williams, Gordon H., Witte, Daniel R., Wood, Andrew R., Xie, Weijia, Boehnke, Michael, Cooper, Cyrus, Ferrucci, Luigi, Froguel, Philippe, Groop, Leif, Kao, W.H. Linda, Vollenweider, Peter, Walker, Mark, Watanabe, Richard M., Pedersen, Oluf, Meigs, James B., Ingelsson, Erik, Barroso, Inês, Florez, Jose C., Franks, Paul W., Dupuis, Josée, Wareham, Nicholas J., Langenberg, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331745/
https://www.ncbi.nlm.nih.gov/pubmed/22415877
http://dx.doi.org/10.2337/db11-0973