Glycotoxin and Autoantibodies Are Additive Environmentally Determined Predictors of Type 1 Diabetes: A Twin and Population Study

In type 1 diabetes, diabetes-associated autoantibodies, including islet cell antibodies (ICAs), reflect adaptive immunity, while increased serum N(ε)-carboxymethyl-lysine (CML), an advanced glycation end product, is associated with proinflammation. We assessed whether serum CML and autoantibodies pr...

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Detalles Bibliográficos
Autores principales: Beyan, Huriya, Riese, Harriette, Hawa, Mohammed I., Beretta, Guisi, Davidson, Howard W., Hutton, John C., Burger, Huibert, Schlosser, Michael, Snieder, Harold, Boehm, Bernhard O., Leslie, R. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Immunology and Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331747/
https://www.ncbi.nlm.nih.gov/pubmed/22396204
http://dx.doi.org/10.2337/db11-0971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331747/
https://www.ncbi.nlm.nih.gov/pubmed/22396204
http://dx.doi.org/10.2337/db11-0971

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