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Glycotoxin and Autoantibodies Are Additive Environmentally Determined Predictors of Type 1 Diabetes: A Twin and Population Study

In type 1 diabetes, diabetes-associated autoantibodies, including islet cell antibodies (ICAs), reflect adaptive immunity, while increased serum N(ε)-carboxymethyl-lysine (CML), an advanced glycation end product, is associated with proinflammation. We assessed whether serum CML and autoantibodies pr...

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Detalles Bibliográficos
Autores principales:	Beyan, Huriya, Riese, Harriette, Hawa, Mohammed I., Beretta, Guisi, Davidson, Howard W., Hutton, John C., Burger, Huibert, Schlosser, Michael, Snieder, Harold, Boehm, Bernhard O., Leslie, R. David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331747/ https://www.ncbi.nlm.nih.gov/pubmed/22396204 http://dx.doi.org/10.2337/db11-0971

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