Deletion of the Androgen Receptor in Adipose Tissue in Male Mice Elevates Retinol Binding Protein 4 and Reveals Independent Effects on Visceral Fat Mass and on Glucose Homeostasis

Testosterone deficiency is epidemic in obese ageing males with type 2 diabetes, but the direction of causality remains unclear. Testosterone-deficient males and global androgen receptor (AR) knockout mice are insulin resistant with increased fat, but it is unclear whether AR signaling in adipose tis...

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Detalles Bibliográficos
Autores principales: McInnes, Kerry J., Smith, Lee B., Hunger, Nicole I., Saunders, Philippa T.K., Andrew, Ruth, Walker, Brian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331763/
https://www.ncbi.nlm.nih.gov/pubmed/22415878
http://dx.doi.org/10.2337/db11-1136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331763/
https://www.ncbi.nlm.nih.gov/pubmed/22415878
http://dx.doi.org/10.2337/db11-1136

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