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Deletion of the Androgen Receptor in Adipose Tissue in Male Mice Elevates Retinol Binding Protein 4 and Reveals Independent Effects on Visceral Fat Mass and on Glucose Homeostasis
Testosterone deficiency is epidemic in obese ageing males with type 2 diabetes, but the direction of causality remains unclear. Testosterone-deficient males and global androgen receptor (AR) knockout mice are insulin resistant with increased fat, but it is unclear whether AR signaling in adipose tis...
Autores principales: | McInnes, Kerry J., Smith, Lee B., Hunger, Nicole I., Saunders, Philippa T.K., Andrew, Ruth, Walker, Brian R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331763/ https://www.ncbi.nlm.nih.gov/pubmed/22415878 http://dx.doi.org/10.2337/db11-1136 |
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