HDLs Protect Pancreatic β-Cells Against ER Stress by Restoring Protein Folding and Trafficking

Endoplasmic reticulum (ER) homeostasis alteration contributes to pancreatic β-cell dysfunction and death and favors the development of diabetes. In this study, we demonstrate that HDLs protect β-cells against ER stress induced by thapsigargin, cyclopiazonic acid, palmitate, insulin overexpression, a...

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Detalles Bibliográficos
Autores principales: Pétremand, Jannick, Puyal, Julien, Chatton, Jean-Yves, Duprez, Jessica, Allagnat, Florent, Frias, Miguel, James, Richard W., Waeber, Gérard, Jonas, Jean-Christophe, Widmann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331764/
https://www.ncbi.nlm.nih.gov/pubmed/22399686
http://dx.doi.org/10.2337/db11-1221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331764/
https://www.ncbi.nlm.nih.gov/pubmed/22399686
http://dx.doi.org/10.2337/db11-1221

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