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The Human GLP-1 Analog Liraglutide and the Pancreas: Evidence for the Absence of Structural Pancreatic Changes in Three Species

Glucagon-like peptide (GLP)-1 analogs have been implicated as a risk factor for pancreatitis in humans. We investigated whether liraglutide, the once-daily human GLP-1 analog, induces pancreatitis in rats, mice, and monkeys. Pancreata from mice, rats, and nonhuman primates were examined macro- and m...

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Detalles Bibliográficos
Autores principales: Nyborg, Niels C.B., Mølck, Anne-Marie, Madsen, Lars W., Bjerre Knudsen, Lotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331765/
https://www.ncbi.nlm.nih.gov/pubmed/22338093
http://dx.doi.org/10.2337/db11-0936