Cargando…

Clamp loader ATPases and the evolution of DNA replication machinery

Clamp loaders are pentameric ATPases of the AAA+ family that operate to ensure processive DNA replication. They do so by loading onto DNA the ring-shaped sliding clamps that tether the polymerase to the DNA. Structural and biochemical analysis of clamp loaders has shown how, despite differences in c...

Descripción completa

Detalles Bibliográficos
Autores principales: Kelch, Brian A, Makino, Debora L, O'Donnell, Mike, Kuriyan, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331839/
https://www.ncbi.nlm.nih.gov/pubmed/22520345
http://dx.doi.org/10.1186/1741-7007-10-34