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Clamp loader ATPases and the evolution of DNA replication machinery

Clamp loaders are pentameric ATPases of the AAA+ family that operate to ensure processive DNA replication. They do so by loading onto DNA the ring-shaped sliding clamps that tether the polymerase to the DNA. Structural and biochemical analysis of clamp loaders has shown how, despite differences in c...

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Detalles Bibliográficos
Autores principales:	Kelch, Brian A, Makino, Debora L, O'Donnell, Mike, Kuriyan, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331839/ https://www.ncbi.nlm.nih.gov/pubmed/22520345 http://dx.doi.org/10.1186/1741-7007-10-34

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