Optogenetic stimulation of a hippocampal engram activates fear memory recall

A specific memory is thought to be encoded by a sparse population of neurons(1,2). These neurons can be tagged during learning for subsequent identification(3) and manipulation(4,5,6). Moreover, their ablation or inactivation results in reduced memory expression, suggesting their necessity in mnemon...

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Detalles Bibliográficos
Autores principales: Liu, Xu, Ramirez, Steve, Pang, Petti T., Puryear, Corey B., Govindarajan, Arvind, Deisseroth, Karl, Tonegawa, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331914/
https://www.ncbi.nlm.nih.gov/pubmed/22441246
http://dx.doi.org/10.1038/nature11028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331914/
https://www.ncbi.nlm.nih.gov/pubmed/22441246
http://dx.doi.org/10.1038/nature11028

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