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Programmed Death-1 and Its Ligand Are Novel Immunotolerant Molecules Expressed on Leukemic B Cells in Chronic Lymphocytic Leukemia

Programmed death-1 (PD-1) is an immunoreceptor predominantly expressed on exhausted T cells, which through an interaction with its ligand (PD-L1), controls peripheral tolerance by limiting effector functions of T lymphocytes. qRT-PCR for PD-1, PD-L1 and their splicing forms as well as flow cytometri...

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Detalles Bibliográficos
Autores principales: Grzywnowicz, Maciej, Zaleska, Joanna, Mertens, Daniel, Tomczak, Waldemar, Wlasiuk, Paulina, Kosior, Kamila, Piechnik, Agnieszka, Bojarska-Junak, Agnieszka, Dmoszynska, Anna, Giannopoulos, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331976/
https://www.ncbi.nlm.nih.gov/pubmed/22532845
http://dx.doi.org/10.1371/journal.pone.0035178