Cysteamine Suppresses Invasion, Metastasis and Prolongs Survival by Inhibiting Matrix Metalloproteinases in a Mouse Model of Human Pancreatic Cancer

BACKGROUND: Cysteamine, an anti-oxidant aminothiol, is the treatment of choice for nephropathic cystinosis, a rare lysosomal storage disease. Cysteamine is a chemo-sensitization and radioprotection agent and its antitumor effects have been investigated in various tumor cell lines and chemical induce...

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Detalles Bibliográficos
Autores principales: Fujisawa, Toshio, Rubin, Benjamin, Suzuki, Akiko, Patel, Prabhudas S., Gahl, William A., Joshi, Bharat H., Puri, Raj K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332081/
https://www.ncbi.nlm.nih.gov/pubmed/22532830
http://dx.doi.org/10.1371/journal.pone.0034437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332081/
https://www.ncbi.nlm.nih.gov/pubmed/22532830
http://dx.doi.org/10.1371/journal.pone.0034437

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