Alterations of Gene Expression and Glutamate Clearance in Astrocytes Derived from an MeCP2-Null Mouse Model of Rett Syndrome

Rett syndrome (RTT) is a neurodevelopmetal disorder associated with mutations in the methyl-CpG–binding protein 2 (MeCP2) gene. MeCP2-deficient mice recapitulate the neurological degeneration observed in RTT patients. Recent studies indicated a role of not only neurons but also glial cells in neuron...

Descripción completa

Detalles Bibliográficos
Autores principales: Okabe, Yasunori, Takahashi, Tomoyuki, Mitsumasu, Chiaki, Kosai, Ken-ichiro, Tanaka, Eiichiro, Matsuishi, Toyojiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332111/
https://www.ncbi.nlm.nih.gov/pubmed/22532851
http://dx.doi.org/10.1371/journal.pone.0035354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332111/
https://www.ncbi.nlm.nih.gov/pubmed/22532851
http://dx.doi.org/10.1371/journal.pone.0035354

Ejemplares similares