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Alterations of Gene Expression and Glutamate Clearance in Astrocytes Derived from an MeCP2-Null Mouse Model of Rett Syndrome

Rett syndrome (RTT) is a neurodevelopmetal disorder associated with mutations in the methyl-CpG–binding protein 2 (MeCP2) gene. MeCP2-deficient mice recapitulate the neurological degeneration observed in RTT patients. Recent studies indicated a role of not only neurons but also glial cells in neuron...

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Detalles Bibliográficos
Autores principales:	Okabe, Yasunori, Takahashi, Tomoyuki, Mitsumasu, Chiaki, Kosai, Ken-ichiro, Tanaka, Eiichiro, Matsuishi, Toyojiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332111/ https://www.ncbi.nlm.nih.gov/pubmed/22532851 http://dx.doi.org/10.1371/journal.pone.0035354

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