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Hyperosmolarity potentiates toxic effects of benzalkonium chloride on conjunctival epithelial cells in vitro

PURPOSE: Benzalkonium chloride (BAK), the most commonly used preservative in eye drops, is known to induce ocular irritation symptoms and dry eye in long-term treated patients and animal models. As tear film hyperosmolarity is diagnostic of some types of dry eye disease, we determined in vitro on co...

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Detalles Bibliográficos
Autores principales: Clouzeau, Chloé, Godefroy, David, Riancho, Luisa, Rostène, William, Baudouin, Christophe, Brignole-Baudouin, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332130/
https://www.ncbi.nlm.nih.gov/pubmed/22529703