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Integrin Signaling in Cancer Cell Survival and Chemoresistance

Resistance to apoptosis and chemotherapy is a hallmark of cancer cells, and it is a critical factor in cancer recurrence and patient relapse. Extracellular matrix (ECM) via its receptors, the integrins, has emerged as a major pathway contributing to cancer cell survival and resistance to chemotherap...

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Detalles Bibliográficos
Autores principales: Aoudjit, Fawzi, Vuori, Kristiina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332161/
https://www.ncbi.nlm.nih.gov/pubmed/22567280
http://dx.doi.org/10.1155/2012/283181