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GSK-3β and memory formation

In Alzheimer’s disease (AD), tau hyperphosphorylation and neurofibrillary tangle (NFT) formation are strongly associated with dementia, a characteristic and early feature of this disease. Glycogen synthase kinase 3β (GSK-3β) is a pivotal kinase in both the normal and pathological phosphorylation of...

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Detalles Bibliográficos
Autor principal: Takashima, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332229/
https://www.ncbi.nlm.nih.gov/pubmed/22536172
http://dx.doi.org/10.3389/fnmol.2012.00047