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NOV/CCN3 attenuates inflammatory pain through regulation of matrix metalloproteinases-2 and -9

BACKGROUND: Sustained neuroinflammation strongly contributes to the pathogenesis of pain. The clinical challenge of chronic pain relief led to the identification of molecules such as cytokines, chemokines and more recently matrix metalloproteinases (MMPs) as putative therapeutic targets. Evidence po...

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Detalles Bibliográficos
Autores principales: Kular, Lara, Rivat, Cyril, Lelongt, Brigitte, Calmel, Claire, Laurent, Maryvonne, Pohl, Michel, Kitabgi, Patrick, Melik-Parsadaniantz, Stéphane, Martinerie, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332238/
https://www.ncbi.nlm.nih.gov/pubmed/22353423
http://dx.doi.org/10.1186/1742-2094-9-36