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Secondary Metabolites from Plants Inhibiting ABC Transporters and Reversing Resistance of Cancer Cells and Microbes to Cytotoxic and Antimicrobial Agents

Fungal, bacterial, and cancer cells can develop resistance against antifungal, antibacterial, or anticancer agents. Mechanisms of resistance are complex and often multifactorial. Mechanisms include: (1) Activation of ATP-binding cassette (ABC) transporters, such as P-gp, which pump out lipophilic co...

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Detalles Bibliográficos
Autores principales: Wink, Michael, Ashour, Mohamed L., El-Readi, Mahmoud Zaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332394/
https://www.ncbi.nlm.nih.gov/pubmed/22536197
http://dx.doi.org/10.3389/fmicb.2012.00130