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Pharmacodynamic analysis of the analgesic effect of capsaicin 8% patch (Qutenza™) in diabetic neuropathic pain patients: detection of distinct response groups

Treatment of chronic pain is associated with high variability in the response to pharmacological interventions. A mathematical pharmacodynamic model was developed to quantify the magnitude and onset/offset times of effect of a single capsaicin 8% patch application in the treatment of painful diabeti...

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Detalles Bibliográficos
Autores principales: Martini, Christian, Yassen, Ashraf, Olofsen, Erik, Passier, Paul, Stoker, Malcom, Dahan, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333798/
https://www.ncbi.nlm.nih.gov/pubmed/22536092
http://dx.doi.org/10.2147/JPR.S30406