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Pharmacodynamic analysis of the analgesic effect of capsaicin 8% patch (Qutenza™) in diabetic neuropathic pain patients: detection of distinct response groups
Treatment of chronic pain is associated with high variability in the response to pharmacological interventions. A mathematical pharmacodynamic model was developed to quantify the magnitude and onset/offset times of effect of a single capsaicin 8% patch application in the treatment of painful diabeti...
Autores principales: | Martini, Christian, Yassen, Ashraf, Olofsen, Erik, Passier, Paul, Stoker, Malcom, Dahan, Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333798/ https://www.ncbi.nlm.nih.gov/pubmed/22536092 http://dx.doi.org/10.2147/JPR.S30406 |
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