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Exacerbation of collagen induced arthritis by Fcγ receptor targeted collagen peptide due to enhanced inflammatory chemokine and cytokine production

Antibodies specific for bovine type II collagen (CII) and Fcγ receptors play a major role in collagen-induced arthritis (CIA), a mouse model of rheumatoid arthritis (RA). Our aim was to clarify the mechanism of immune complex-mediated inflammation and modulation of the disease. CII pre-immunized DBA...

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Detalles Bibliográficos
Autores principales: Szarka, Eszter, Neer, Zsuzsa, Balogh, Péter, Ádori, Monika, Angyal, Adrienn, Prechl, József, Kiss, Endre, Kövesdi, Dorottya, Sármay, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333823/
https://www.ncbi.nlm.nih.gov/pubmed/22532778
http://dx.doi.org/10.2147/BTT.S29749