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MRE11 and RAD50, but not NBS1, are essential for gene targeting in the moss Physcomitrella patens
The moss Physcomitrella patens is unique among plant models for the high frequency with which targeted transgene insertion occurs via homologous recombination. Transgene integration is believed to utilize existing machinery for the detection and repair of DNA double-strand breaks (DSBs). We undertoo...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333855/ https://www.ncbi.nlm.nih.gov/pubmed/22210882 http://dx.doi.org/10.1093/nar/gkr1272 |