Cdx2 homeoprotein inhibits non-homologous end joining in colon cancer but not in leukemia cells

Cdx2, a gene of the paraHox cluster, encodes a homeodomain transcription factor that plays numerous roles in embryonic development and in homeostasis of the adult intestine. Whereas Cdx2 exerts a tumor suppressor function in the gut, its abnormal ectopic expression in acute leukemia is associated to...

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Detalles Bibliográficos
Autores principales: Renouf, Benjamin, Soret, Christine, Saandi, Thoueiba, Delalande, François, Martin, Elisabeth, Vanier, Marie, Duluc, Isabelle, Gross, Isabelle, Freund, Jean-Noël, Domon-Dell, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333856/
https://www.ncbi.nlm.nih.gov/pubmed/22189105
http://dx.doi.org/10.1093/nar/gkr1242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333856/
https://www.ncbi.nlm.nih.gov/pubmed/22189105
http://dx.doi.org/10.1093/nar/gkr1242

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