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Template-dependent polymerization across discontinuous templates by the heterodimeric primase from the hyperthermophilic archaeon Sulfolobus solfataricus

The eukaryotic-like primase from the hyperthermophilic archaeon Sulfolobus solfataricus (SsoPriSL) exhibits a range of activities including template-dependent de novo primer synthesis, primer extension and template-independent terminal nucleotidyl transfer using either rNTPs or dNTPs. Remarkably, th...

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Detalles Bibliográficos
Autores principales: Hu, Jinchuan, Guo, Li, Wu, Kangyun, Liu, Bing, Lang, Shiwei, Huang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333859/
https://www.ncbi.nlm.nih.gov/pubmed/22189102
http://dx.doi.org/10.1093/nar/gkr1256