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Sensitive and label-free biosensing of RNA with predicted secondary structures by a triplex affinity capture method

A novel biosensing approach for the label-free detection of nucleic acid sequences of short and large lengths has been implemented, with special emphasis on targeting RNA sequences with secondary structures. The approach is based on selecting 8-aminoadenine-modified parallel-stranded DNA tail-clamps...

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Detalles Bibliográficos
Autores principales: Carrascosa, Laura G., Gómez-Montes, S., Aviñó, A., Nadal, A., Pla, M., Eritja, R., Lechuga, L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333861/
https://www.ncbi.nlm.nih.gov/pubmed/22241768
http://dx.doi.org/10.1093/nar/gkr1304