Role of polynucleotide kinase/phosphatase in mitochondrial DNA repair

Mutations in mitochondrial DNA (mtDNA) are implicated in a broad range of human diseases and in aging. Compared to nuclear DNA, mtDNA is more highly exposed to oxidative damage due to its proximity to the respiratory chain and the lack of protection afforded by chromatin-associated proteins. While r...

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Detalles Bibliográficos
Autores principales: Tahbaz, Nasser, Subedi, Sudip, Weinfeld, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333865/
https://www.ncbi.nlm.nih.gov/pubmed/22210862
http://dx.doi.org/10.1093/nar/gkr1245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333865/
https://www.ncbi.nlm.nih.gov/pubmed/22210862
http://dx.doi.org/10.1093/nar/gkr1245

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