Cargando…

Role of polynucleotide kinase/phosphatase in mitochondrial DNA repair

Mutations in mitochondrial DNA (mtDNA) are implicated in a broad range of human diseases and in aging. Compared to nuclear DNA, mtDNA is more highly exposed to oxidative damage due to its proximity to the respiratory chain and the lack of protection afforded by chromatin-associated proteins. While r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tahbaz, Nasser, Subedi, Sudip, Weinfeld, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333865/ https://www.ncbi.nlm.nih.gov/pubmed/22210862 http://dx.doi.org/10.1093/nar/gkr1245

Ejemplares similares

Phosphorylation of polynucleotide kinase/ phosphatase by DNA-dependent protein kinase and ataxia-telangiectasia mutated regulates its association with sites of DNA damage
por: Zolner, Angela E., et al.
Publicado: (2011)

Independent mechanisms of stimulation of polynucleotide kinase/phosphatase by phosphorylated and non-phosphorylated XRCC1
por: Lu, Meiling, et al.
Publicado: (2010)

Bacillus subtilis polynucleotide phosphorylase 3′-to-5′ DNase activity is involved in DNA repair
por: Cardenas, Paula P., et al.
Publicado: (2009)

DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair
por: Abdou, Ismail, et al.
Publicado: (2015)

Mapping the interactions of the single-stranded DNA binding protein of bacteriophage T4 (gp32) with DNA lattices at single nucleotide resolution: polynucleotide binding and cooperativity
por: Jose, Davis, et al.
Publicado: (2015)

Polynucleotide phosphorylase exonuclease and polymerase activities on single-stranded DNA ends are modulated by RecN, SsbA and RecA proteins
por: Cardenas, Paula P., et al.
Publicado: (2011)

Protein phosphatase 1 and phosphatase 1 nuclear targeting subunit-dependent regulation of DNA-dependent protein kinase and non-homologous end joining
por: Zhu, Songli, et al.
Publicado: (2017)

PP4 phosphatase cooperates in recombinational DNA repair by enhancing double-strand break end resection
por: Villoria, María Teresa, et al.
Publicado: (2019)

Membrane association of mitochondrial DNA facilitates base excision repair in mammalian mitochondria
por: Boesch, Pierre, et al.
Publicado: (2010)

ATR kinase activation in G1 phase facilitates the repair of ionizing radiation-induced DNA damage
por: Gamper, Armin M., et al.
Publicado: (2013)

SIRT1 regulates DNA damage signaling through the PP4 phosphatase complex
por: Rasti, George, et al.
Publicado: (2023)

Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function
por: Szczesny, Bartosz, et al.
Publicado: (2014)

Oxidative stress during mitochondrial biogenesis compromises mtDNA integrity in growing hearts and induces a global DNA repair response
por: Pohjoismäki, Jaakko L. O., et al.
Publicado: (2012)

The role of Holliday junction resolvases in the repair of spontaneous and induced DNA damage
por: Agmon, Neta, et al.
Publicado: (2011)

Barrier-to-autointegration-factor (Banf1) modulates DNA double-strand break repair pathway choice via regulation of DNA-dependent kinase (DNA-PK) activity
por: Burgess, Joshua T, et al.
Publicado: (2021)

THO complex deficiency impairs DNA double-strand break repair via the RNA surveillance kinase SMG-1
por: Kamp, Juliette A, et al.
Publicado: (2022)

Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex
por: Dutta, Arijit, et al.
Publicado: (2017)

The role of SLX4 and its associated nucleases in DNA interstrand crosslink repair
por: Hoogenboom, Wouter S, et al.
Publicado: (2019)

Cell cycle stage-specific roles of Rad18 in tolerance and repair of oxidative DNA damage
por: Yang, Yang, et al.
Publicado: (2013)

A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair
por: Tomida, Junya, et al.
Publicado: (2013)

Evolutionary patterns of DNA base composition and correlation to polymorphisms in DNA repair systems
por: Li, Xianran, et al.
Publicado: (2015)

The ATPase activity of Fml1 is essential for its roles in homologous recombination and DNA repair
por: Nandi, Saikat, et al.
Publicado: (2012)

Rad52 SUMOylation affects the efficiency of the DNA repair
por: Altmannova, Veronika, et al.
Publicado: (2010)

Lesion-specific DNA-binding and repair activities of human O(6)-alkylguanine DNA alkyltransferase
por: Melikishvili, Manana, et al.
Publicado: (2012)

An interplay of the base excision repair and mismatch repair pathways in active DNA demethylation
por: Grin, Inga, et al.
Publicado: (2016)

Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair
por: Kalasova, Ilona, et al.
Publicado: (2020)

Yields of damage to C4′ deoxyribose and to pyrimidines in pUC18 by the direct effect of ionizing radiation
por: Peoples, Anita R., et al.
Publicado: (2012)

The accessory subunit of mitochondrial DNA polymerase γ determines the DNA content of mitochondrial nucleoids in human cultured cells
por: Di Re, M., et al.
Publicado: (2009)

Inhibition of DNA damage repair by artificial activation of PARP with siDNA
por: Croset, Amelie, et al.
Publicado: (2013)

RAD51 interconnects between DNA replication, DNA repair and immunity
por: Bhattacharya, Souparno, et al.
Publicado: (2017)

Nucleotide excision repair of abasic DNA lesions
por: Kitsera, Nataliya, et al.
Publicado: (2019)

Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts
por: Çağlayan, Melike, et al.
Publicado: (2017)

Timely termination of repair DNA synthesis by ATAD5 is important in oxidative DNA damage-induced single-strand break repair
por: Park, Su Hyung, et al.
Publicado: (2021)

Rad9 plays an important role in DNA mismatch repair through physical interaction with MLH1
por: He, Wei, et al.
Publicado: (2008)

Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks
por: Woo, Tai-Ting, et al.
Publicado: (2020)

Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
por: Zhao, Junhua, et al.
Publicado: (2009)

DNA damage signaling induced by the G-quadruplex ligand 12459 is modulated by PPM1D/WIP1 phosphatase
por: Douarre, Céline, et al.
Publicado: (2013)

Stress-inducible NHEJ in bacteria: function in DNA repair and acquisition of heterologous DNA
por: Dupuy, Pierre, et al.
Publicado: (2019)

Catalytically inactive DNA ligase IV promotes DNA repair in living cells
por: Goff, Noah J, et al.
Publicado: (2022)

Oxidative stress induces degradation of mitochondrial DNA
por: Shokolenko, Inna, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_hj94mdj0irtpur8jrugd14cv4j