Cargando…
Role of replication protein A as sensor in activation of the S-phase checkpoint in Xenopus egg extracts
Uncoupling between DNA polymerases and helicase activities at replication forks, induced by diverse DNA lesions or replication inhibitors, generate long stretches of primed single-stranded DNA that is implicated in activation of the S-phase checkpoint. It is currently unclear whether nucleation of t...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333866/ https://www.ncbi.nlm.nih.gov/pubmed/22187152 http://dx.doi.org/10.1093/nar/gkr1241 |