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Role of replication protein A as sensor in activation of the S-phase checkpoint in Xenopus egg extracts

Uncoupling between DNA polymerases and helicase activities at replication forks, induced by diverse DNA lesions or replication inhibitors, generate long stretches of primed single-stranded DNA that is implicated in activation of the S-phase checkpoint. It is currently unclear whether nucleation of t...

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Detalles Bibliográficos
Autores principales:	Recolin, Bénédicte, Van Der Laan, Siem, Maiorano, Domenico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333866/ https://www.ncbi.nlm.nih.gov/pubmed/22187152 http://dx.doi.org/10.1093/nar/gkr1241

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