Topo IV is the topoisomerase that knots and unknots sister duplexes during DNA replication

DNA topology plays a crucial role in all living cells. In prokaryotes, negative supercoiling is required to initiate replication and either negative or positive supercoiling assists decatenation. The role of DNA knots, however, remains a mystery. Knots are very harmful for cells if not removed effic...

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Detalles Bibliográficos
Autores principales: López, Virginia, Martínez-Robles, María-Luisa, Hernández, Pablo, Krimer, Dora B., Schvartzman, Jorge B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333868/
https://www.ncbi.nlm.nih.gov/pubmed/22187153
http://dx.doi.org/10.1093/nar/gkr1237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333868/
https://www.ncbi.nlm.nih.gov/pubmed/22187153
http://dx.doi.org/10.1093/nar/gkr1237

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