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MATS: a Bayesian framework for flexible detection of differential alternative splicing from RNA-Seq data

Ultra-deep RNA sequencing has become a powerful approach for genome-wide analysis of pre-mRNA alternative splicing. We develop MATS (multivariate analysis of transcript splicing), a Bayesian statistical framework for flexible hypothesis testing of differential alternative splicing patterns on RNA-Se...

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Detalles Bibliográficos
Autores principales: Shen, Shihao, Park, Juw Won, Huang, Jian, Dittmar, Kimberly A., Lu, Zhi-xiang, Zhou, Qing, Carstens, Russ P., Xing, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333886/
https://www.ncbi.nlm.nih.gov/pubmed/22266656
http://dx.doi.org/10.1093/nar/gkr1291