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Serial MRI Features of Canine GM1 Gangliosidosis: A Possible Imaging Biomarker for Diagnosis and Progression of the Disease

GM1 gangliosidosis is a fatal neurodegenerative lysosomal storage disease caused by an autosomal recessively inherited deficiency of β-galactosidase activity. Effective therapies need to be developed to treat the disease. In Shiba Inu dogs, one of the canine GM1 gangliosidosis models, neurological s...

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Detalles Bibliográficos
Autores principales: Hasegawa, Daisuke, Yamato, Osamu, Nakamoto, Yuya, Ozawa, Tsuyoshi, Yabuki, Akira, Itamoto, Kazuhito, Kuwabara, Takayuki, Fujita, Michio, Takahashi, Kimimasa, Mizoguchi, Shunta, Orima, Hiromitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific World Journal 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334264/
https://www.ncbi.nlm.nih.gov/pubmed/22536126
http://dx.doi.org/10.1100/2012/250197