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Regulation of calcium in pancreatic α- and β-cells in health and disease

The glucoregulatory hormones insulin and glucagon are released from the β- and α-cells of the pancreatic islets. In both cell types, secretion is secondary to firing of action potentials, Ca(2+)-influx via voltage-gated Ca(2+)-channels, elevation of [Ca(2+)](i) and initiation of Ca(2+)-dependent exo...

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Detalles Bibliográficos
Autores principales: Rorsman, Patrik, Braun, Matthias, Zhang, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334273/
https://www.ncbi.nlm.nih.gov/pubmed/22177710
http://dx.doi.org/10.1016/j.ceca.2011.11.006