Cargando…
Regulation of calcium in pancreatic α- and β-cells in health and disease
The glucoregulatory hormones insulin and glucagon are released from the β- and α-cells of the pancreatic islets. In both cell types, secretion is secondary to firing of action potentials, Ca(2+)-influx via voltage-gated Ca(2+)-channels, elevation of [Ca(2+)](i) and initiation of Ca(2+)-dependent exo...
Autores principales: | Rorsman, Patrik, Braun, Matthias, Zhang, Quan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334273/ https://www.ncbi.nlm.nih.gov/pubmed/22177710 http://dx.doi.org/10.1016/j.ceca.2011.11.006 |
Ejemplares similares
-
Glucagon secretion from pancreatic α-cells
por: Briant, Linford, et al.
Publicado: (2016) -
Regulated Exocytosis of GABA-containing Synaptic-like Microvesicles in Pancreatic β-cells
por: Braun, Matthias, et al.
Publicado: (2004) -
γ-Aminobutyric Acid (GABA) Is an Autocrine Excitatory Transmitter in Human Pancreatic β-Cells
por: Braun, Matthias, et al.
Publicado: (2010) -
Oscillations, Intercellular Coupling, and Insulin Secretion in Pancreatic β Cells
por: MacDonald, Patrick E, et al.
Publicado: (2006) -
Type 2 Diabetes Susceptibility Gene TCF7L2 and Its Role in β-Cell Function
por: Gloyn, Anna L., et al.
Publicado: (2009)