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Genetic polymorphism of the iron-regulatory protein-1 and -2 genes in age-related macular degeneration

Iron can be involved in the pathogenesis of AMD through the oxidative stress because it may catalyze the Haber–Weiss and Fenton reactions converting hydrogen peroxide to free radicals, which can induce cellular damage. We hypothesized that genetic polymorphism in genes related to iron metabolism may...

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Detalles Bibliográficos
Autores principales: Synowiec, Ewelina, Pogorzelska, Magdalena, Blasiak, Janusz, Szaflik, Jerzy, Szaflik, Jacek Pawel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334491/
https://www.ncbi.nlm.nih.gov/pubmed/22331484
http://dx.doi.org/10.1007/s11033-012-1539-6