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Genetic polymorphism of the iron-regulatory protein-1 and -2 genes in age-related macular degeneration
Iron can be involved in the pathogenesis of AMD through the oxidative stress because it may catalyze the Haber–Weiss and Fenton reactions converting hydrogen peroxide to free radicals, which can induce cellular damage. We hypothesized that genetic polymorphism in genes related to iron metabolism may...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334491/ https://www.ncbi.nlm.nih.gov/pubmed/22331484 http://dx.doi.org/10.1007/s11033-012-1539-6 |