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Assessing the Accuracy and Power of Population Genetic Inference from Low-Pass Next-Generation Sequencing Data

Next-generation sequencing (NGS) technologies have made it possible to address population genetic questions in almost any system, but high error rates associated with such data can introduce significant biases into downstream analyses, necessitating careful experimental design and interpretation in...

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Detalles Bibliográficos
Autores principales: Crawford, Jacob E., Lazzaro, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334522/
https://www.ncbi.nlm.nih.gov/pubmed/22536207
http://dx.doi.org/10.3389/fgene.2012.00066