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Predicting responses to sunitinib using single nucleotide polymorphisms: Progress and recommendations for future trials
Targeted therapy with tyrosine kinase inhibitors has led to a substantial improvement in the standard of care for patients with advanced or metastatic clear cell renal cell carcinoma. Because the mechanism of action, metabolism and transport of tyrosine kinase inhibitors can affect outcome and toxic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334544/ https://www.ncbi.nlm.nih.gov/pubmed/22212486 http://dx.doi.org/10.1186/gm295 |