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Drug transporter regulation in tumors by DNA methylation

Epigenetic alterations, such as aberrant DNA methylation, are a hallmark of cancer. DNA hypermethylation of the promoter region affects, for example, the expression of tumor suppressor genes and is associated with their transcriptional silencing in tumors. A recent report has provided evidence for e...

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Detalles Bibliográficos
Autores principales: Zolk, Oliver, Fromm, Martin F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334558/
https://www.ncbi.nlm.nih.gov/pubmed/22293136
http://dx.doi.org/10.1186/gm309