Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase

BACKGROUND: Orthology is a central tenet of comparative genomics and ortholog identification is instrumental to protein function prediction. Major advances have been made to determine orthology relations among a set of homologous proteins. However, they depend on the comparison of individual sequenc...

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Detalles Bibliográficos
Autores principales: Szklarczyk, Radek, Wanschers, Bas FJ, Cuypers, Thomas D, Esseling, John J, Riemersma, Moniek, van den Brand, Mariël AM, Gloerich, Jolein, Lasonder, Edwin, van den Heuvel, Lambert P, Nijtmans, Leo G, Huynen, Martijn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334569/
https://www.ncbi.nlm.nih.gov/pubmed/22356826
http://dx.doi.org/10.1186/gb-2012-13-2-r12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334569/
https://www.ncbi.nlm.nih.gov/pubmed/22356826
http://dx.doi.org/10.1186/gb-2012-13-2-r12

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