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Dissecting the regulatory architecture of gene expression QTLs

BACKGROUND: Expression quantitative trait loci (eQTLs) are likely to play an important role in the genetics of complex traits; however, their functional basis remains poorly understood. Using the HapMap lymphoblastoid cell lines, we combine 1000 Genomes genotypes and an extensive catalogue of human...

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Detalles Bibliográficos
Autores principales: Gaffney, Daniel J, Veyrieras, Jean-Baptiste, Degner, Jacob F, Pique-Regi, Roger, Pai, Athma A, Crawford, Gregory E, Stephens, Matthew, Gilad, Yoav, Pritchard, Jonathan K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334587/
https://www.ncbi.nlm.nih.gov/pubmed/22293038
http://dx.doi.org/10.1186/gb-2012-13-1-r7